Pure Natural Products

The NatProd Collection (800 Compounds)
Our natural product collection is derived from resources exclusive to MDSI and our affiliate Gaia Chemical Corporation. The content has evolved from 480 compounds at its introduction to 800 compounds today. All are fully characterized according to literature reports, and meet our criteria of a minimum of 95% purity. We select the compounds included in the NatProd Collection on the basis of structural and chemical class. At present approximately 75% of the collection encompasses:

• alkaloids (16%),
• flavanoids (12%),
• sterols/triterpenes (12%),
• diterpenes/sesquiterpenes (10%),
• benzophenones/chalcones/stilbenes (10%),
• limonoids/quassinoids (9%), and
• chromones/coumarins (6%).

The remainder of the collection includesquinones/quinonemethides, benzofurans/benzopyrans, rotenoids/xanthones, carbohydrates, and benztropolones/depsides/depsidones, in descending order.

References to the use of the NatProd Collection:
A Vogt, A Tamewitz, J Skoko, RP Sikorski, KA Giuliano and JS Lazo, The Benzo[c]phenanthridine Alkaloid, Sanguinarine, Is a Selective, Cell-active Inhibitor of Mitogen-activated Protein Kinase Phosphatase-1, J Biol Chem 280:19078 (2005).

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