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Celebrating 22 Years of Customer Service

Over the past decade, MicroSource has led the industry in the development of collections of bioactive substances in the search of new therapeutic agents. There are many substances in the literature that have shown biological promise but never reached marketable status. Today's plethora of new assays based on the Human genome and advances in our understanding of biochemical processes have led us to gather a collection of these "under developed" entities and make them available for HTS discovery. Our DISCOVER collection is comprised of 560 compounds that have shown biological potential in peer-reviewed publications but have never led to their development as drugs in human diseases. We offer these to you as a supplement to our drug collections to expand the scope of your inquiry.



US Drug Collection
An important collection of 1280 drugs that have reached clinical trial stages in the USA. Each compound has been assigned USAN or USP status and is included in the USP Dictionary (U.S. Pharmacopeia, 2012), the authorized list of established names for drugs in the USA. References

International Drug Collection
This collection comprises 320 drugs that are marketed in Europe and/or Asia but have not been introduced in the US. Such compounds have received INN, BAN and/or JAN designations, and are listed in the Index Nominum, the International Drug Directory. References


Pharmakon 1600
PHARMAKON 1600 is a combination of all the compounds from the US and International Drug Collections. Unlike competitive products, all compounds within the PHARMAKON 1600 Collection have reached clinical evaluation and not simply demonstrated biological activity experimentally. Most of the constituent drugs are still in the market. Data provided for each compound define its structure, CAS #, formula, molecular weight, biological profile and generic & market name. Literature references to use and toxicology are also included.

The term PHARMAKON is an ancient Greek term that refers to medicinal preparations that were used to alleviate a patient's symptoms and, on occasion, cure the disease. PHARMAKON also encompassed poisons that were believed to provide therapeutic benefit with judicious use. The term still reflects the character of today's medicines and a fitting title for this remarkable collection.


The NatProd Collection
Our natural product collection of 800 compounds is derived from commercial sources including our affiliate Gaia Chemical Corporation. All are fully characterized according to literature reports, and meet our criteria of a minimum of 95% purity. We select the compounds included in the NatProd Collection on the basis of structural and chemical class. At present approximately 75% of the collection encompasses: alkaloids (16%), flavanoids (12%), sterols/triterpenes (12%), diterpenes/sesquiterpenes (10%), benzophenones/chalcones/stilbenes (10%), limonoids/quassinoids (9%), and chromones/coumarins (6%).The remainder of the collection includesquinones/quinonemethides, benzofurans/benzopyrans, rotenoids/xanthones, carbohydrates, and benztropolones/depsides/depsidones, in descending order. References

For bulk natural products please visit www.gaiachem.com


Spectrum includes all of the compounds in the Discover, Pharmakon and NatProd Collections. References

The Killer Plates
Reference collection of 160 synthetic and natural toxic substances (plates A and B). An unprecedented opportunity to tease and test your assay. Inhibitors of DNA/RNA synthesis, cellular respiration, membrane integrity and much more. References